Classic Southern meatloaf recipe kicked up with a twist. Your favorite salsa is added to seasoned ground beef for a comforting holiday meat loaf or easy no fuss weeknight dinner.

This meatloaf is moist on the inside and highly flavored with an amazing ketchup based glaze. The salsa is used in both the glaze and the meatloaf for added flavor and moisture. It not only tastes good, but looks jest as good.
MOOD MUSIC
MEATLOAF INGREDIENTS
- Ground Beef or Chuck
- Eggs
- Onions
- Bread Crumbs
- Parsley
- Ketchup
- Worcestershire Sauce
- Salsa
- Brown Sugar
- Salt
- Pepper
SOUTHERN MEATLOAF COOKING INSTRUCTIONS
Prepare the meatloaf
Add the eggs to the ground beef and mix in. Then add spices, onions, parsley, bread crumbs, Worcestershire Sauce, and salsa.

Mix all the ingredients well then shape into your preferred mold. Use your hands or use a bowl to shape. Place molded meatloaf into baking dish.

Make the glaze
Mix ketchup, brown sugar, and remaining salsa in a bowl. Apply the glaze on top of the meatloaf.

Bake the meatloaf
Pre-heat oven to 400 degrees F. Place meatloaf on the middle rack uncovered and bake 30 minutes.
Remove the meatloaf. Turn oven to highest broil settings and place the rack on the top level. Add the meatloaf and broil 5-10 minutes until glaze caramelizes.
COOKING CONSIDERATIONS
Southern meatloaf goes well with classic mashed potatoes, mac and cheese, and green beans.
Avoid lean ground meat. Lean meat equals dry meat loaf! Go for higher fat ground beef.
The wet ingredients (salsa, eggs, and Worcestershire sauce) play important roles. Besides flavor, they are essential moistening agents.
Dice the onions as evenly as possible so there is consistency in texture throughout the meatloaf.
For additional flavor saute your vegetables first.
Don't tightly pack your meatloaf into your baking dish. Make sure there is ample room around the meatloaf. If packed too tight the loaf will actually "steam" and thus rob you of both texture and flavor.
Make sure the meat has fully reached room temperature before cooking.
Choose your favorite salsa or hot sauce. I used a homemade Caribbean style hot sauce, but it packed some heat. A good tomato-based salsa works well. If you have one you really like then use it.
Southern meatloaf recipes typically call for diced bell peppers, but I chose to forgo them since the salsa I used had green chilis in it.
Don't overmix the meatloaf, or handle too heavy-handed. Doing so will disturb the texture and lead to a more rubbery loaf that is tough to chew.
Rest time is as essential as the actual cooking so don't be in too much of a rush to cut into the loaf.
To freeze the whole meatloaf and reserve for later consumption, wrap it tightly in a couple of layers of aluminum foil and then either place in a large freezer bag or use a vacuum sealer. To reheat let it thaw in the refrigerator over night then, sit out to achieve room temperature status, then slowly heat in the oven at around 275 degrees.

MORE RECIPES
make this recipe
If you make this Southern meat loaf recipe or any other from the site, please come back and leave me a comment below with your feedback. Definitely take a photo of the dish and be sure to tag #foodfidelity so that I can see them.
You can also keep up with my food exploits as well as original recipes! You can find me on Instagram, Facebook, Twitter, and Pinterest. If you like any of the music you find on the site, visit me at Spotify to find curated monthly playlists.
Ingredients
For the meatloaf
- 2 lb. ground chuck
- 1 cup onion diced
- 2 eggs
- 1 cup bread crumbs
- 1 tablespoon Worcestershire sauce
- ½ cup salsa
- 2 teaspoon kosher or sea salt
- 2 teaspoon black pepper
- 2 tablespoon fresh parsley chopped with no stems
For the glaze
- ½ cup ketchup
- ¼ cup salsa
- 2 tablespoon brown sugar
Instructions
Make the glaze
- Mix all three ingredients well in a mixing bowl and set aside
Make the meatloaf
- Place ground beef in a large mixing bowl. Add the eggs and massage the eggs fully into the meat.
- Add the bread crumbs, seasoning, onions, parsley, salsa, and Worcestershire sauce mixing it all well.
- Using your hands or a large mold, shape the meatloaf mixture and then add to a small baking dish.
- Layer the glaze on top.
- Pre-heat oven to 400 degrees F with the rack in the made. Add the meatloaf and cook for about 30 minutes.
- Remove the meatloaf from the oven. Adjust the rack to top level and then change the oven settings to broil at the highest temperature.
- Add the meatloaf back to the oven and broil 5-10 minutes until the glaze caramelizes. It will be black in a few spots but that’s fine.
- Remove from the oven and let the meatloaf rest at least 5 minutes.
Natalie
Monday 28th of September 2020
I haven't made meatloaf in ages! Thanks for reminder and this lovely recipe. Meat looks delicious and juicy. I will give your recipe a try.
Sam
Monday 28th of September 2020
Wow that meatloaf looks so moist and juicy! I can’t believe I have never tried making meatloaf myself. You make it sound so easy.
Jo
Sunday 27th of September 2020
I love how simple but amazing that meatloaf looks. It's flavor profile is amazing! What a juicy looking meatloaf.
Uma
Sunday 27th of September 2020
Looks juicy and i like the final color of the loaf!I never tried Worcestershire sauce, next time i want to try that sauce :)
Marisa F. Stewart
Sunday 27th of September 2020
This certainly looks like one tasty meatloaf. I love how you don't pack it like a snowball - making it tough and dense. And the wow factor of the salsa will make this one meatloaf we'll want to make frequently. I hope we have some left over because I bet it will make one great sandwich.